When auscultating the heart of a 68-year-old man, the physician detected a splitting of the first heart sound in the area of the apex of the heart. What valve has a pathology in this case, which can be heard by the physician?

• A. Tricuspid valve
• B. Valve of the superior vena cava
• C. Bicuspid valve
• D. Pulmonary valve
• E. Aortic valve